Category: Mitosis

BCSC have been purified from breast cancer patient samples as well while from breast tumor cell lines [7, 12, 16-20, 23]

BCSC have been purified from breast cancer patient samples as well while from breast tumor cell lines [7, 12, 16-20, 23]. Improved PI3K/AKT activity correlates with a poor prognosis of breast cancer patients [25, 26] and is described as a major pathway conferring resistance to standard therapies in multiple tumor types, including breast cancer [25, […]

Indeed, landmark studies by Clark, Cnop, and colleagues uncover that human cells and cells may also be very long lived (24, 25)

Indeed, landmark studies by Clark, Cnop, and colleagues uncover that human cells and cells may also be very long lived (24, 25). diabetes results from autoimmune destruction of pancreatic cells, which decreases the total number of cells capable of secreting insulin and other Coumarin 7 hormones (1). Normal glucose homeostasis becomes disrupted in type 1 […]

Cells were centrifuged at 1000 rpm for 5 min, and excess media were aspirated

Cells were centrifuged at 1000 rpm for 5 min, and excess media were aspirated. TUGUL modifies the kinesin motor protein, KIF5B, and that TUG proteolysis is required to load GLUT4 onto these motors. Insulin stimulates TUG proteolytic processing independently PMPA of phosphatidylinositol 3-kinase. In nonadipocytes, TUG cleavage can be reconstituted by transfection of Usp25m, but […]