Category: Mu Opioid Receptors

CX-5461 repressed the growth of established oncogene [2]

CX-5461 repressed the growth of established oncogene [2]. display a strong correlation between high-risk disease, manifestation, poor survival, and ribosome biogenesis in neuroblastoma individuals. Treatment of neuroblastoma cells with quarfloxin or CX-5461, two small molecule inhibitors of RNA polymerase I, suppressed MycN manifestation, induced DNA damage, and triggered p53 followed by cell cycle arrest or […]