Category: NADPH Oxidase

For example, Ann and colleagues18 demonstrated that PKCmediated autophagy during acute hypoxic stress by phosphorylating/activating JNK1, whereas Ozpolat suppressed autophagy in pancreatic cancer cells by inducing tissue transglutaminase

For example, Ann and colleagues18 demonstrated that PKCmediated autophagy during acute hypoxic stress by phosphorylating/activating JNK1, whereas Ozpolat suppressed autophagy in pancreatic cancer cells by inducing tissue transglutaminase. In this study, we have identified PKCas a critical negative regulator of autophagy in both and experimental models of cisplatin. serine-473 by PKCinhibitor rottlerin with cisplatin protected […]

Asterisks indicate a statistical difference (** < 0

Asterisks indicate a statistical difference (** < 0.01, *** < 0.001, obtained using Dunnetts test against wild-type ezrin). 2.5. to a significant buildup of actin fibers, a decrease in nuclear volume, and an increase in cytoskeletal stiffness. Finally, cell transfection with the dominant negative ezrin FERM domain induces significant morphological and nuclear changes and affects […]