Category: mGlu2 Receptors

Three independent 100-ns MD simulations in aqueous solution were conducted starting from the crystal structure of each protein

Three independent 100-ns MD simulations in aqueous solution were conducted starting from the crystal structure of each protein. development, CHARMM-GUI has been widely used in the biomolecular modeling and simulation community, and it has grown into a platform of web-based tools for simulations: for free energy perturbation molecular dynamics (FEP/MD) simulations for protein-ligand binding affinity […]

Supplementary MaterialsFIGURE S1: High temozolomide (TMZ) concentrations significantly reduce glioblastoma cell line viability

Supplementary MaterialsFIGURE S1: High temozolomide (TMZ) concentrations significantly reduce glioblastoma cell line viability. time-dependent manner. High TMZ concentrations with IC50 DPG was able to induce U87MG (C) and T98G (D) cell viability reduction in incubation times (24, 48, 72, and 96 h) lower than those observed when used alone in a dose- and time-dependent manner. […]